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Clinical Trial Details for A Study of LY3375880 in Adults With Moderate-to-Severe Atopic Dermatitis

Eli Lilly and Company
NCT ID: NCT03831191
Last Updated: June 3, 2019

The Study at a Glance

  • Status: Recruiting
  • Phase: Phase 2
  • Gender: All
  • Age: 18 Years - N/A
  • Condition: Atopic Dermatitis
  • Study Type: Interventional
  • Intervention:
  • Lead Sponsor: Eli Lilly and Company
  • Location: Not Provided

Official Title

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Evaluate the Efficacy and Safety of LY3375880 in Adult Subjects With Moderate-to-Severe Atopic Dermatitis: The ADmIRe Study


The reason for this study is to see if the study drug LY3375880 is safe and effective in adults with moderate-to-severe atopic dermatitis (AD).


Ages Eligible for Study

18 Years to N/A

Sexes Eligible for Study


Accepts Healthy Volunteers



Inclusion Criteria:

– Participants must have diagnosis of AD >= 12 months according to the American Academy
of Dermatology criteria.

– Participants must have moderate to severe AD at screening and randomization.

– Participants must have inadequate response to topical medications within 6 months of
screening (or history of intolerance).

Exclusion Criteria:

– Participants must not have concurrent treatment with topical or systemic treatments
for AD.

Additional Information, Locations & Contacts

Sponsors & Collaborators

Eli Lilly and Company


Study Director: Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)

Eli Lilly and Company

Please refer to this study by its ClinicalTrials.gov identifier: NCT03831191



Tien Q. Nguyen, MD inc. DBA First OC Dermatology

Fountain Valley, California 92708

United States

Dermatology Research Associates

Los Angeles, California 90045

United States

Quest Dermatology Research

Northridge, California 91324

United States

Integrative Skin Science and Research

Sacramento, California 95815

United States

Arlington Dermatology

Rolling Meadows, Illinois 60008

United States

The South Bend Clinic

South Bend, Indiana 46617

United States

Dermatology and Skin Cancer Specialists

Rockville, Maryland 20850

United States

ActivMed Practices & Research, Inc

Portsmouth, New Hampshire 03801

United States

Piedmont Plastic Surgery and Dermatology

Charlotte, North Carolina 28277

United States

Wilmington Health Associates

Wilmington, North Carolina 28401

United States

Hightower Clinical Trial Services

Norman, Oklahoma 73072

United States

Oregon Dermatology and Research Center

Portland, Oregon 97210

United States

Clinical Partners LLC

Johnston, Rhode Island 02919

United States

Center for Clinical Studies

Houston, Texas 77004

United States

Virginia Clinical Research

Norfolk, Virginia 23502

United States

Ordensklinikum Linz GmbH - Elisabethinen

Linz, Oberösterreich 4020


Universitätsklinikum Graz

Graz, Steiermark 8036


Sozialmed. Zentrum Ost - Donauspital

Wien, 1220


The Guenther Dermatology Research Centre

London, Ontario N6A 3H7


Clintrial, s.r.o.

Praha 10, Hl. M. Praha 100 00


Sanatorium Profesora Arenbergera

Praha 1, 110 00


CHU de Nice Hopital de L'Archet

Nice cedex 3, 06202


Hopital Larrey

Toulouse cedex 9, 31059


Oroshaza Varosi Onkormanyzat Korhaza

Oroshaza, Bekes 5901


Allergo-Derm Bakos Kft

Szolnok, Jasz-Nagykun-Szolnok 5000


UNO Medical Trials Kft.

Budapest, 1135


Veszprem Megyei Csolnoky Ferenc Korhaz

Veszprem, 8200


Istituto Clinico Humanitas

Rozzano, Milano 20089


Policlinico di Tor Vergata

Roma, 00133


Dip.to Med. Sperimentale -Polic.Umberto I -Univ. La Sapienza

Roma, 00161


Yasumoto Dermatology Clinic

Chikushino, Fukuoka 818 0083


Takagi Dermatological Clinic

Obihiro, Hokkaido 080-0013


Kobe University Hospital

Kobe, Hyogo 650-0017


Meiwa Hospital

Nishinomiya, Hyogo 663-8186


Kyoto Prefectural University of Medicine

Kyoto-shi, Kyoto 602-8566


Oita University Hospital

Yufu-shi, Oita 8795593


Kume Clinic

Nishi-ku Sakai-shi, Osaka 593-8324


Sumire Dermatology Clinic

Edogawa-ku, Tokyo 133-0057


Matsuda Tomoko Dematological Clinic

Fukuoka, 819 0167


Office of Dr. Samuel Sanchez PSC

Caguas, 00727

Puerto Rico

Office of Dr. Alma M. Cruz

Carolina, 00985

Puerto Rico

Ponce School of Medicine CAIMED Center

Ponce, 00716

Puerto Rico

Clinical Research Puerto Rico, Inc.

San Juan, 00909

Puerto Rico

GCM Medical Group PSC

San Juan, 00917

Puerto Rico

Hospital Universitari de Bellvitge

L'Hospitalet de Llobregat, Barcelona 08907


Clinica Universitaria De Navarra

Pamplona, Navarra 31008


Hospital Universitario La Paz

Madrid, 28046