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Clinical Trial Details for A Study of LY3375880 in Adults With Moderate-to-Severe Atopic Dermatitis


Eli Lilly and Company
NCT ID: NCT03831191
Last Updated: June 3, 2019

The Study at a Glance

  • Status: Recruiting
  • Phase: Phase 2
  • Gender: All
  • Age: 18 Years - N/A
  • Condition: Atopic Dermatitis
  • Study Type: Interventional
  • Intervention:
  • Lead Sponsor: Eli Lilly and Company
  • Location: Not Provided

Official Title

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Evaluate the Efficacy and Safety of LY3375880 in Adult Subjects With Moderate-to-Severe Atopic Dermatitis: The ADmIRe Study

Purpose

The reason for this study is to see if the study drug LY3375880 is safe and effective in adults with moderate-to-severe atopic dermatitis (AD).

Eligibility

Ages Eligible for Study

18 Years to N/A

Sexes Eligible for Study

All

Accepts Healthy Volunteers

No

Criteria

Inclusion Criteria:

– Participants must have diagnosis of AD >= 12 months according to the American Academy
of Dermatology criteria.

– Participants must have moderate to severe AD at screening and randomization.

– Participants must have inadequate response to topical medications within 6 months of
screening (or history of intolerance).

Exclusion Criteria:

– Participants must not have concurrent treatment with topical or systemic treatments
for AD.

Additional Information, Locations & Contacts

Sponsors & Collaborators

Eli Lilly and Company

Investigators

Study Director: Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)

Eli Lilly and Company

Please refer to this study by its ClinicalTrials.gov identifier: NCT03831191

Location

Contacts

Tien Q. Nguyen, MD inc. DBA First OC Dermatology

Fountain Valley, California 92708

United States

Dermatology Research Associates

Los Angeles, California 90045

United States

Quest Dermatology Research

Northridge, California 91324

United States

Integrative Skin Science and Research

Sacramento, California 95815

United States

Arlington Dermatology

Rolling Meadows, Illinois 60008

United States

The South Bend Clinic

South Bend, Indiana 46617

United States

Dermatology and Skin Cancer Specialists

Rockville, Maryland 20850

United States

ActivMed Practices & Research, Inc

Portsmouth, New Hampshire 03801

United States

Piedmont Plastic Surgery and Dermatology

Charlotte, North Carolina 28277

United States

Wilmington Health Associates

Wilmington, North Carolina 28401

United States

Hightower Clinical Trial Services

Norman, Oklahoma 73072

United States

Oregon Dermatology and Research Center

Portland, Oregon 97210

United States

Clinical Partners LLC

Johnston, Rhode Island 02919

United States

Center for Clinical Studies

Houston, Texas 77004

United States

Virginia Clinical Research

Norfolk, Virginia 23502

United States

Ordensklinikum Linz GmbH - Elisabethinen

Linz, Oberösterreich 4020

Austria

Universitätsklinikum Graz

Graz, Steiermark 8036

Austria

Sozialmed. Zentrum Ost - Donauspital

Wien, 1220

Austria

The Guenther Dermatology Research Centre

London, Ontario N6A 3H7

Canada

Clintrial, s.r.o.

Praha 10, Hl. M. Praha 100 00

Czechia

Sanatorium Profesora Arenbergera

Praha 1, 110 00

Czechia

CHU de Nice Hopital de L'Archet

Nice cedex 3, 06202

France

Hopital Larrey

Toulouse cedex 9, 31059

France

Oroshaza Varosi Onkormanyzat Korhaza

Oroshaza, Bekes 5901

Hungary

Allergo-Derm Bakos Kft

Szolnok, Jasz-Nagykun-Szolnok 5000

Hungary

UNO Medical Trials Kft.

Budapest, 1135

Hungary

Veszprem Megyei Csolnoky Ferenc Korhaz

Veszprem, 8200

Hungary

Istituto Clinico Humanitas

Rozzano, Milano 20089

Italy

Policlinico di Tor Vergata

Roma, 00133

Italy

Dip.to Med. Sperimentale -Polic.Umberto I -Univ. La Sapienza

Roma, 00161

Italy

Yasumoto Dermatology Clinic

Chikushino, Fukuoka 818 0083

Japan

Takagi Dermatological Clinic

Obihiro, Hokkaido 080-0013

Japan

Kobe University Hospital

Kobe, Hyogo 650-0017

Japan

Meiwa Hospital

Nishinomiya, Hyogo 663-8186

Japan

Kyoto Prefectural University of Medicine

Kyoto-shi, Kyoto 602-8566

Japan

Oita University Hospital

Yufu-shi, Oita 8795593

Japan

Kume Clinic

Nishi-ku Sakai-shi, Osaka 593-8324

Japan

Sumire Dermatology Clinic

Edogawa-ku, Tokyo 133-0057

Japan

Matsuda Tomoko Dematological Clinic

Fukuoka, 819 0167

Japan

Office of Dr. Samuel Sanchez PSC

Caguas, 00727

Puerto Rico

Office of Dr. Alma M. Cruz

Carolina, 00985

Puerto Rico

Ponce School of Medicine CAIMED Center

Ponce, 00716

Puerto Rico

Clinical Research Puerto Rico, Inc.

San Juan, 00909

Puerto Rico

GCM Medical Group PSC

San Juan, 00917

Puerto Rico

Hospital Universitari de Bellvitge

L'Hospitalet de Llobregat, Barcelona 08907

Spain

Clinica Universitaria De Navarra

Pamplona, Navarra 31008

Spain

Hospital Universitario La Paz

Madrid, 28046

Spain