The Effect of Emollient Therapy on the Skin Barrier (EES)


Oregon Health and Science University

Information provided by

Eric Simpson, MD, MCR, Oregon Health and Science University Identifier:



The goal of this study is to understand the effects of emollients (moisturizers) on the skin of young children and adults.


Ages Eligible for Study:     3 months and older
Genders Eligible for Study:           Both
Accepts Healthy Volunteers:        Yes


Inclusion Criteria:

Pediatric- enrollment in the BEEP emollient intervention study, overall good health.
Adult- History of atopic dermatitis, 12 years or older, 4×4 cm non-lesional skin on both inner forearms, no condition that would make the use of 4 emollients harmful for subject

Exclusion Criteria:
Pediatric- History of or being evaluated for other skin barrier disease, active skin infection, receiving phototherapy, immunodeficiency or severe genetic skin disease, medical problem making use of emollients inadvisable, other medical problem that study investigator deems may increase risk of adverse event.
Adult- Use of topical steroids on inner forearms or immunosuppressive medications in last 4 weeks, receiving phototherapy or systemic immunosuppressive therapy in 3 months prior to participation.


Portland, Oregon (Oregon Health and Sciences University)

Principal Investigator

Eric Simpson, MD, MCR (Oregon Health and Science University)