Vtama (tapinarof) cream (1%) is an aryl hydrocarbon receptor (AHR) agonist approved by the FDA for the topical treatment of atopic dermatitis in adults and children 2 years of age and older.
Together, you and your healthcare provider can determine if Vtama is an appropriate treatment option.
Vtama is not a topical steroid. It works by specifically binding to and activating the aryl hydrocarbon receptor (AHR) to downregulate inflammatory pathways and oxidative stress, and increase expression of proteins involved in skin barrier function.
Vtama is applied as a thin film directly to the affected areas of skin once daily.1
In the two ADORING Phase 3 clinical trials for Vtama, after 8 weeks of continuous use2:
The most common adverse reactions from clinical trials (incidence greater than/equal to 1%) are upper or lower respiratory tract infections, folliculitis (inflamed hair follicles), headache, asthma, vomiting, ear infections, extremity or stomach pain. Most adverse reactions were mild or moderate in severity.
Topical corticosteroids work non-specifically to reduce inflammation in the skin by preventing cells from producing inflammation-causing chemicals that are released in response to a variety of different triggers.
Vtama works in a more targeted manner to activate the aryl hydrocarbon receptor (AHR) to downregulate inflammatory pathways and improve barrier function. Because Vtama is not a topical corticosteroid, it is able to be used over a longer period of time,2,3 and on body areas that are more delicate or have thinner skin, such as the face, genitals, or skin folds, where topical corticosteroid use is not preferred.
Atopic dermatitis is a chronic skin disease that can affect everyone differently. The length of therapy with Vtama should be discussed with your healthcare provider.
Vtama is FDA-approved for children ages 2 years and older.
Cost depends on your health insurance coverage for prescriptions. Dermavant, an Organon company, the company that makes Vtama, has a program to help with your copay costs if needed. You can apply at MyVTAMA or call 347.532.5250 (9 a.m. – 7 p.m. ET).
It’s important to talk to your doctor about how atopic dermatitis affects your skin and other aspects of your life. Together, you and your healthcare provider can determine if Vtama is an appropriate treatment option.
Vtama is available by prescription only. Talk to your healthcare provider and visit Vtama.com to learn more.
Talk to your healthcare provider about using Vtama with other prescription and over-the-counter therapies for atopic dermatitis. Vtama has not been studied in combination with other topical, oral or injectible atopic dermatitis medications.
Be sure your doctor knows all medications you are using for your atopic dermatitis as well as other medical conditions.