Over-the-counter (OTC) shampoos are products you can purchase without a prescription from a doctor. OTC shampoos have gentle formulas that help minimize irritation and support the scalp barrier for people with eczema.
Gentle, fragrance-free
These shampoos avoid fragrances, dyes and harsh detergents — common triggers for eczema flares. They’re formulated with mild cleansing agents and designed specifically for sensitive skin. When shopping, look for products labeled “fragrance-free” rather than “unscented,” as unscented products may still contain masking fragrances that can cause irritation.
Moisturizing and barrier support
Often formulated with ingredients like colloidal oatmeal, aloe vera or glycerin, these shampoos help hydrate and soothe the scalp while supporting the skin’s natural barrier function. Many of these products are also sulfate-free, which helps reduce dryness that can worsen eczema symptoms. These moisturizing ingredients work to calm irritated skin while gently cleansing the hair and scalp.
Medicated
For people with eczema who also have overlapping scalp conditions like seborrheic dermatitis, healthcare providers may recommend medicated shampoos. These specialized products contain active ingredients to help manage inflammation and flaking. Common active ingredients may include coal tar, salicylic acid, zinc pyrithione, selenium sulfide and ketoconazole. It’s important to use these products only under the guidance of your healthcare provider.
